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Year : 2022, Volume : 12, Issue : 3
First page : ( 117) Last page : ( 146)
Print ISSN : 2231-3419. Online ISSN : 2454-7611. Published online : 2022  20.
Article DOI : 10.5958/2454-7611.2022.00012.1

Tetrazole scaffold as resourceful building blocks in chemistry and approaching their biological activities: A brief review

Agarwal Pranshi, Chauhan Kuldeep*

Department of Applied Science and Humanities, Invertis University, Bareilly-243123, Uttar Pradesh, India

*Corresponding author email id: kuldeep.c@invertis.org

Online Published on 20 March, 2023.

Received:  28  ,  2022; Accepted:  21  ,  2022.

Abstract

Recent studies revealed that the contribution of the different bioactive scaffolds in one structure creates modern drugs/compounds with unique synergistic biological activities. In this regard, thanks to the interesting biological and medicinal properties of tetrazole skeletons. The tetrazole nucleus represents, among the class of heterocycles, a very important scaffold to obtain molecules with biological activities. A review of literature revealed how such kinds of heterocycles, coming from natural and synthetic source, are associated with a wide range of biological activities.

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Keywords

Tetrazole, Biological activities, Antimalarial, Antifungal, Antitubercular.

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