A comprehensive review on the transmission, pathogenesis, and prevention of monkey pox Sharma Neha1,*, Sharma Sakshi2, Bala Madhu1, Rana Ritesh1, Sharma Neelam1 1Department of Pharmaceutics, Himachal Institute of Pharmaceutical Education and Research, Nadaun, HP 2Department of Pharmaceutics, Chandigarh Engineering College, CGC, Jhanjeri, Mohali *Corresponding Author E-mail: imnehavk@gmail.com
Online published on 4 May, 2024. Abstract Manily the cases of monkeypox connected to the 2022 breakout are being reported in nations throughout Europe and the Western Hemisphere, where it was formerly endemic to parts of Africa. Numerous groups are working on contact-tracing initiatives, but it is still unclear what started this outbreak. The monkeypox virus disease is a zoonotic viruses is a member of the orthopoxvirus genus and belonging to family poxiviridae. Following the eradication of smallpox worldwide in the 1970s, occurrences of monkeypox attracted attention on a global scale. The monkeypox virus could be protected against by the smallpox vaccine. Monkeypox instances increased once the smallpox vaccine was no longer administered. Monkeypox did not really receive widespread notice until the 2003 US outbreak. Despite the name "monkeypox," the virus did not originate in monkeys. The virus has been linked to a numeral of rodents and small animals, but the exact source of monkeypox is still unknown. The viral infection was originally noticed in macaque monkeys, hence the term "monkeypox." Although transmission of monkeypox from person to person is extremely uncommon, it is frequently assign to respiratory secretions or closely contacted with mucocutaneous abrasion of the contaminated person. Now present no designated cure for contaminated person, although supportive therpy may be used to relieve symptoms; in extremely severe cases, medications such tecovirimat may be used. Because there are no precise recommendations for symptom alleviation, many treatments are arbitrary. In light of the current outbreaks worldwide, we provide updated information on monkeypox for healthcare professionals in this review. Top Keywords Monkeypox, Orthopoxvirus, Zoonotic, Replication, Viremia. Top |