Basement membrane in health and disease-an enigma to histopathologist Biradar Vijaykumar1,*, Shrivastav Namita2, Shree Priya3, Sinha Rakhee4, Chaurasia Akhilanand5 1Reader, Dept. of Oral Pathology, Vananchal Dental College & Hospital, Garhwa, Jharkhand 2Senior Lecturer, Dept. of Oral Pathology, Vananchal Dental College & Hospital, Garhwa, Jharkhand 3Senior Lecturer, Dept. of Oral Pathology, Vananchal Dental College & Hospital, Garhwa, Jharkhand 4Senior Lecturer, Dept. of Oral Pathology, Vananchal Dental College & Hospital, Garhwa, Jharkhand 5Associate Professor, Dept. of Oral Medicine & Radiology, King's George Medical University, Lucknow, Uttar Pradesh, India *Corresponding Author: Email: drvijay06_biradar@yahoo.com
Online published on 3 January, 2019. Abstract Basement membrane is known to play a role in the pathogenesis of inflammatory, tumor invasion, metastases and autoimmune diseases. A basement membrane (BM) is a thick sheet of extracellular matrix molecules, upon which epithelial cells attach and form a boundary between epithelium and the connective tissue. It also provides structural support for epithelial, mesothelial, and endothelial cells and surrounds adipocytes, muscles and Schwann cells. This literature review describes terminologies, histology, ultrastructure, molecular aspects, functions and histochemical studies of basement membrane in health and disease. Top Keywords Basement membrane, Extracellular matrix, Health, Disease. Top |