Journal of Innovation in Pharmaceutical Sciences
Year : 2019, Volume : 3, Issue : 2
First page : ( 23) Last page : ( 26)
Online ISSN : 2581-5695.

An overview on Nipah Virus

Sai V Tarun

Guru Nanak Institutions Technical Campus-School of Pharmacy, Ibrahimpatnam, Ranga reddy, Hyderabad, Telangana, India, 501506, tarun25rocks@gmail.com

Online published on 22 January, 2021.

Abstract

NIPAH is a viral zoonotic disease caused by virus named NIPAH of genus henipavirus and of family paramyxoviridae . This disease caused a havoc damage to both animal and human kind. The major outbreak of this disease is by the pteropus species. The disease in humans caused a damage to respiratory and neurological systems in body. The present day advances in technology leads us to easy identification and diagnosis of the deadly disease. The scripps research institute (TSIR) have resolved the structure of key protein in NIPAH virus which could pave a way for development of antibodies against the NiV. The vaccine named “HENDRA-SG” was developed which could medicate the virus .The novel way of delivery of therapy is by “stealth liposomes” which helps in reaching the site of action .The movie named “CONTAGION” is based on global NIPAH outbreak. The drugs such as chloroquine and ribavirin treatment which are popularly known today to treat NIPAH are found worthless in hamster model. The FIVIPIRAVIR (T-705) the potent antiviral drug was efficient in dealing with the disease by inhibiting replication and transcription at micro molecular levels in NIPAH virus. Although many vaccines and drugs are available to NIPAH there is no currently approved vaccines that prevent NIPAH, so I suggest everyone to be attentive in their part as prevention is better than cure.

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Keywords

Nipah Virus, Henipavirus and of family paramyxoviridae.

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