Comparison of total antioxidant capacity in term small for gestational age (SGA) and appropriate for gestational age (AGA) newborns Vaswani N.D.1,*, Lekhwani Seema2, Yadav Jaivinder3, Dugesar Rajendra4, Yadav Aparna5 1Professor, Dept. of Pediatrics, UHSR, PGIMS, Rohtak 2Associate Professor, Dept. of Biochemistry, UHSR, BPSGMC, Sonepat 3Assistant Professor, Dept.of Pediatrics, PGIMER, Chandigarh 4Nodal Officer, Dept. of Pediatrics, Civil Hospital, Gohana 5Professor, Dept. of Microbiology, UHSR, PGIMS, Rohtak, Haryana *Corresponding Author: Email: ndvaswani@hotmail.com
Online published on 23 February, 2018. Abstract Background Total antioxidant capacity (TAC) is a measure of oxidative stress. Oxidative stress has been implicated in the pathogenesis of many diseases of newborns. The objective of this study was to estimate total antioxidant capacity in term small for gestational age (SGA) newborns and compare it with term appropriate for gestational age (AGA) newborns. The study was done at a tertiary level teaching hospital Materials & Methods 82 newborns (Term AGA 46 and Term SGA 36) were enrolled. Cord blood was taken and TAC of serum was determined by TAC assay kit (from Labor Diagnostika, Germany) Result There was no significant difference in the total antioxidant capacity of the term AGA and SGA groups. There was significant difference in the mean birth weight of the AGA and SGA groups. Also, the ponderal index was significantly different. Conclusion Weight for gestational age in term newborns do not significantly affect total antioxidant capacity. Top Keywords TAC, SGA, AGA. Top |