The Bacteriological Profile and Antibiogram of Post operative/Surgical Site Wound Infections in a Tertiary Care Hospital Pandey Rohit1, Garg S.P2, Dimri Sanjeev2, Varshney Krati3 1Post-Graduate, Department of Microbiology, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh, India 2Professor, Department of Microbiology, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh, India 3Associate Professor, Department of Microbiology, Saraswathi Institute of Medical Sciences, Hapur, Uttar Pradesh, India Online published on 6 April, 2019. Abstract Out of 282 patients having post-operative wound infections, 196 yielded bacterial growth. From 196 patients, 108 (55.1%) were males and 88 (44.9%) were females. Majority of pus samples were from surgical ward 112 (57%) followed by ENT 36(18.3%), Obs&Gynae 24(12.2%), Orthopedics 14(7.1%), Neuro-Surgery, and Burn & plastic Surgery 5 (2.5%) ward together. Gram negative bacteria were seen to be more prevalent 128 (59.2%) as compared to Gram positive bacteria 88 (40.8%). Staphylococcus species 86 (39.8%) were isolated as the major pathogens causing suppurative infection followed by Escheriachia coli 52 (24%), Pseudomonas species 30 (13.8%), Enterobacter species 20 (9.2%), Klebsiella Species 12 (5.5%), Proteus species 8 (3.7%), Acinetobacter species 6 (2.7%) and Enterococcus spp. 2 (0.9%). Gram positive cocci showed high sensitivity to most of the drugs tested such as Vancomycin (100%), Linezolid (100%), Teicoplanin(100%) etc but was found to be highly resistant to Penicillin (100%), Levofloxacin (100%) and Norfloxacin (100%). Pseudomonas spp. showed high sensitivity to Colistin (100%), Polymyxin B (100%) and Amikacin and it was found to be resistant to Ampicillin/sulbactam (100%), Cotrimoxazole (100%). Other Gram negative bacilli showed high sensitivity to Amikacin (92%) and was highly resistant to Aztreonam(100%) and Ceftazidime (100%). Post-operative wound infections are a serious medical Problem that has to be tackled due to its increased morbidity, mortality and medical care costs. An active Surveillance program is recommended. Top Keywords Wound Infection, Post-operative, Infection, Antibiotics susceptibility pattern. Top |