Quantitative and qualitative assessment of diabetic retinopathy after laser treatment Dixit Anukul1,*, Ex-Resident, Yadav Ishan1, Senior Resident, Maurya Rajendra P1, Assistant professor, Singh M. K.1, Professor, Singh S. K.2, Professor 1Dept. of Ophthalmology, Institute of Medical Sciences, BHU, Varanasi 2Dept. of Endocrinology, Institute of Medical Sciences, BHU, Varanasi *Corresponding Author: E-mail: dixit.anukul@gmail.com
Online published on 13 May, 2015. Abstract Aim To investigate the visual and tomographic changes in patients undergoing pan retinal photocoagulation (PRP) for proliferative diabetic retinopathy (PDR) with or without clinically significant macular edema (CSME). Methods This was a prospective, interventional clinical trial including 78 eyes of 78 patients suffering from diabetic retinopathy (DR). All patients were divided into three groups based on the severity of diabetic retinopathy and presence of clinically significant macular edema (CSME). Laser was administered as per the ETDRS standards. Visual acuity (VA), Central macular thickness (CMT), HbA1c and other parameters recorded pre and post laser. Results Mean BCVA decreases from 0.24 to 0.33 at one month (p<0.001) and improved to 0.27 (p>0.05) after 4 months in group 1. In group 2 mean BCVA improved from 0.57 to 0.44 at one month (p<0.001) and further improved to 0.39 at four months (p<0.001). In group 3 it deteriorated from 0.63 to 0.67 (p>0.05) but improved to 0.61 at four months (p>0.05). Mean CMT in group one increased from 235μ to 277μ (p<0.001) but decreased to 253μ (p>0.05). From group 2 mean CMT decreased from 379μ to 325μ at one month (p<0.001) and further decreased to 318μ at four months (p<0.001). In group 3 also mean CMT increased from 374 μ to 382μ at one month (p>0.05) and then decreased to 373μ (p>0.05). Conclusion Laser photocoagulation still remains the gold standard treatment modality in cases of proliferative diabetic retinopathy (PDR) and in treatment of CSME. Top Keywords Pan retinal photocoagulation, proliferative diabetic retinopathy, clinically significant macular edema, Central macular thickness. Top |