Serum Creatinine, Urea Nitrogen And Endogenous Creatinine Clearance Based Glomerular Filtration Rate In Camels To Evaluate Renal Functions Deen Aminu* National Research Centre On Camel, Bikaner, Rajasthan, India *Corresponding Author: aminudeen@scientist.com
Online published on 23 May, 2013. Abstract To evaluate renal functions in camel, the study on profiles like Serum Creatinine (SC), Serum urea nitrogen (SUN), SUN/SC ratio was undertaken in institute’s herd of camels (n=250) (Camelus dromedarius) of all age groups, both sexes and three breeds and in addition Glomerular Filtration rate (GFR) of 18 male camels of 3 breeds (n=6 each) with 6 individual replicates (Total 108 observations) were determined. The values of SC and SUN/SC ratio differ significantly (P< 0.05) between breeds, while those of SUN did not differ (P>0.05). SC was significantly higher in male (P<0.05), while SUN and SUN/SC ratio was significantly higher (P<0.05) in females. The values of SC and SUN/SC ratio did not differed significantly (P>0.05) in different age groups, while SUN differed significantly (P<0.05) between different age groups. Daily Urine Output (UO) and GFR differed significantly (P<0.05) between Bikaneri and Kachchi breeds, while the difference was statistically non-significant (P>0.05) between Bikaneri and Jaisalmeri and Bikaneri and Kachchi breeds. UO and GFR had highly significant (P<0.01) positive correlation ship(r = 0.634). Urine Creatinine (UC) concentration and Total daily Creatinine excreted (TC) did not differ significantly (P<0.05) between breeds. UO and UC had significant (P<0.05) negative correlation ship (r = -0.234). Coefficient of variation within individual for UO, UC, TC and GFR was relatively more indicating less consistency of these profiles. It was felt that under well-monitored and controlled intake of water, GFR could be used to evaluate renal functions in camels. Top Keywords Creatinine clearance, Azotemia, Glomerular Filtration rate. Top |