Wound Healing Activity of Bauhinia purpurea in Albino Wistar Rats Vijayabhaskar K.1,*, Sravanprasad Macharla2, Venkateshwarlu Goli.1, Devi P. Suvarna3, Kumar K. Hemanth4, Sunil J.5 1Venkateshwara Institute of Pharmaceutical Sciences, Nalgonda, Andhra Pradesh-508001 2GBN Institute of Pharmacy, Ghatkeshar, RR District, Andhra Pradesh-501301 3Saipranavi College of Pharmacy, Keesara, RR district, Andhra Pradesh-501301 4Shanta College of Pharmacy, Huzurabad, Karimnagar, Andhra Pradesh-505884 5Anurag College of Pharmacy, Kodada, Nalgonda, Andhra Pradesh-501301 *Corresponding Author E-mail: bhaskar3743@yahoo.com
Online published on 5 June, 2014. Abstract The entire wound healing process is a complex series of events that begins at the moment of injury and can continue for months to years. The stages of wound healing are inflammatory phase, proliferation phase, fibroblastic phase and maturation phase. The objective of our study is to investigate wound healing activity of the methanolic leaf extract of of Bauhinia purpurea Linn in rats.. The leaf extract of Bauhinia purpurea (200 mg/kg/day) was evaluated for its wound healing activity in albino rats using excision and incision wound models. Bauhinia purpurea leaf extract treated animals exhibit 83.42% reduction in wound area when compared to controls which was 76.22%. The extract treated wounds are found to epithelize faster as compared to controls. Significant (p<0.001) increase in granuloma breaking strength (485±34.64) was observed. The povidone iodine ointment was used as standard. Top Keywords Bauhinia purpurea, Wound healing, Excision wound, Incision wound, Povidone iodine. Top |