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Asian Journal of Research in Chemistry
Year : 2008, Volume : 1, Issue : 2
First page : ( 83) Last page : ( 87)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.

Phyto-Physico chemical evaluation, Antioxidant activities and Diuretic activity of Leaves of Lagerstroemia reginae

Kalidas S2, Kameswari B1, Devi P1, Madhumitha B1, Meera R1,*, Merlin NJ3

1K.M.College of Pharmacy, Uthangudi, Madurai -625107

2Bharatidasan University, Trichy

3Annamalai University, Department of Pharmacy, Annamalai Nagar, Chidambaram, Tamilnadu, India

*Corresponding Author E-mail: meeraharsa@yahoo.com

Online published on 13 March, 2013.

Abstract

The present study deals with the preliminary phyto- physicochemical evaluation of a well known folklore remedy for diabetic and inflammation. i.e Lagerstroemia reginae. The standardization is carried out on the basis of physiochemical and phytochemical studies including parameters such as fluorescence characteristics and analysis of inorganic constituents. The study contributes to the development of standardization parameters of herbal drugs used in Indian system of medicine. Thin layer chromatography has been carried out for the entire phytochemical constituent and the inference is noted. It was found that Aminoacids, Tannins, Phytosterols, Flavanoids, Saponins, Triterpenoids and Cardiacglycosides present in the extracts. The diuretic activity was tested in rats at 500 and 1000 mg/Kg, orally and compared with furosemide (20mg/Kg, intraperitoneally) as the standard in aqueous extract. The extract was found to possess significant dose dependent diuretic activity. The antioxidant activity was determined by two in-vitro methods – DPPH and H2O2 radical scavenging.

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Keywords

Lagerstroemia reginae, Phyto-Physiochemical evaluation, Antioxidant activity, Diuretic activity.

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