Stability testing: An Essential study for Vaccine Formulation Development Vyas Amitkumar J., Patel Sinchan M.*, Patel Ashok B., Patel Ajay I., Patel Nilesh K., Shah Suuny, Sheth Devang B. K. Mody Government Pharmacy College, Rajkot-360003, Gujarat, India *Corresponding Author E-mail: patelsivu31@gmail.com
Online Published on 09 June, 2022. Abstract Forced degradation studies are carried out at a more severe condition than accelerated conditions. Stress studies for vaccines are carried out in the early stage of development. By conducting stress studies, we can know the chemical behavior of our molecule which is important while developing formulation, packaging, transportation, storage, etc. there are general regulatory guidelines are available for conducting forced degradation studies but there is no sufficient information provided about how to perform forced degradation studies. Thus, this review discussed stress testing studies of vaccines, mechanisms of vaccine degradation, also analytical methods which are helpful to develop a method for forced degradation. Top Keywords Vaccine, Stability testing of the vaccine, Forced degradation, Analytical Methods, Degradation Mechanism. Top |