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Acute toxicity study of synthesized drug and herbal product Yadav Tanuja*, Rohane Sachin Faculty of Pharmacy, Yashoda Technical Campus, Satara415015, India *Corresponding Author E-mail: tanujayadav711@gmail.com
Online published on 8 July, 2022. Abstract Acute toxicity study describes the adverse effects of a substance that result either from a single exposure or from multiple exposures in a short period of time. Whenever an investigator administered a chemical substance or herbal drug to a biological system different types of interactions can occur and a series of dose-related responses result. In most cases these responses are desired and useful, but there are a number of other effects which are not advantageous. These may or may not be harmful to the patient. Acute toxicity study is involved in estimation of LD50. Also it determines the therapeutic index i.e ratio between the lethal dose and the pharmacologically effective dose in the same strain and species. This article Review the methods so for utilized for the determination of acute toxicity. Top Keywords Acute toxicity study, Therapeutic index, Biological system. Top | | |
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