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Asian Journal of Pharmaceutical Research
Year : 2021, Volume : 11, Issue : 4
First page : ( 239) Last page : ( 241)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.52711/2231-5691.2021.00041

Analgesic activity of hydroalcholic extract of Achyranthes aspera leaves on animal model

Shukla Karunakar Dr.1, Jain Sourabh Dr.1, Patil Narendra1,*, Patil Ketan2, Wagh Kalpesh2

1Department of Pharmacology, Dr. A. P. J. Abdul Kalam UniversityIndore, Madhya PradeshIndia

2Department of Phamaceuices, KVPS Institute of Pharmaceutical Education, Boradi, MaharashtraIndia

*Corresponding Author E-mail: pnarendra101@gmail.com

Online published on 8 July, 2022.

Abstract

Achyranthes aspera L. (Family: Amaranthaceae) is widely used as a medicinal plant. The hydroalcholic extract of Achyranthes aspera L. leaves was screened for its analgesic activity. The dose (200 mg/kg) was tested for analgesic activity using hot plate and Tail flick test in albino mice. The hydroalcholic extract of Achyranthes aspera L. leaves showed maximum analgesic activity in hot plate at reaction time 120 min (7.40±0.08) and tail flick method at reaction time 120 min (6.9±0.06). These study suggest that the hydroalcholic extract of Achyranthes aspera L. could be considered as potential analgesic agent.

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Keywords

Achyranthes aspera L., Analgesic activity, Albino mice, Pentazocine.

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