Spectrum of Systemic Autoimmune Diseases Associated in Patients with Interstitial Lung Disease in a Tertiary Care Centre in Eastern India Singh Pratima1, Padhan Prasanta2 1Assistant Professor, Department of Pulmonary Medicine, Kalinga Institue of Medical Sciences, KIIT University, Bhubaneswar, Odisha, India 2Assistant Professor, Department of Rheumatology, Kalinga Institue of Medical Sciences, KIIT University, Bhubaneswar, Odisha, India Online published on 18 July, 2017. Abstract Introduction The available data on the epidemiology of connective tissue disease associated interstitial lung disease (CTD-ILD) from India is sparse. Hence, the present study was undertaken with the aim to analyze the demographic profile and clinical, radiological and pathological characteristics along with physiological parameters of various subgroups of CTD-ILD patients. Material and method We retrospectively studied 70 patients diagnosed with CTD-ILD during the years May 2013 to April 2016 at Pulmonary Medicine Department at our Institute. Results Mean age at presentation was 44.81 years; females comprised 82.8% of the patients. Prior to presentation at our centre, 10% patients had been treated with anti tubercular therapy due to misdiagnosis of tuberculosis. In the pool of CTD-ILDs analyzed, systemic sclerosis (28.5%) was found to be the most common subgroup, followed by mixed connective tissue disease (MCTD)(25.7%). Cough (85.7%) was the most common presenting symptom; exertional dyspnoea was found in 71.4% of patients. The most common pattern on chest roentgenogram was reticular/reticulo-nodular pattern (50%) and on HRCT Non specific Interstitial Pneumonitis (NSIP) (85.7%). Conclusions We found systemic sclerosis followed by MCTD, NSIP to be the most common CTD-ILDs in eastern India. ILDs are still frequently misdiagnosed as TB, and increased awareness, education and diagnostic facilities are required to diagnose CTD-ILDs at an early stage. Top Keywords Connective tissue disease, Interstitial lung disease, Non specific Interstitial Pneumonitis. Top |