A Comparative Study of Post-Mortem Pupillary Reactivity using Pilocarpine Eye Drop Solution Dwivedi Shivam1, Chauhan Monika2,*, Kumath Manish3, Panga Surya Kiran4 1Ph.D. Research Scholar, Division of Forensic Science, School of Biomedical Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India 2Professor, Division of Forensic Science, School of Basic and Applied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India 3Professor, Department of Forensic Medicine and Toxicology, VMMC-Safdarjung Hospital, New Delhi, India 4Senior Resident, Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences (AIIMS), New Delhi, India *Corresponding Author, Dr. Monika Chauhan, Professor, Email: monika.chauhan@galgotiasuniversity.edu.in
Online Published on 12 January, 2024. Abstract Post-mortem pupillary reactivity to various pharmacological substances is an emerging method to determine the time since death in the early Post-mortem period. For many years, scientists are constantly trying to develop this method more accurately and precisely using mydriatic or mioticsubstances and also trying to rule out the possibility of fallacious factors. Recently, pilocarpine eye drop is the focal point of the researchers to make this method more accurate and cost-effective. However, post-mortem pupillary reactivity to pilocarpine solution simultaneously in both the eyes has not been mentioned yet. The objective of the present work is to test and provide evidence of the effectiveness of post-mortem pupillary reactivity of both the eyes simultaneously to pilocarpine eye drop in the Indian population. Eyes of 250 deceased individuals with known Post-mortem interval was instilled with 2% pilocarpine eye drops and changes in pupil diameter were measured using ImageJ freeware. The author observed no statistically significant difference between the reactivity of the left and right eye (p = 0.4446, at á < .05).Based on our observation, we concluded that right eye and left eye react identically. However, left eye gave better reactivity than right eye in more number of cases. Hence left eye can be used to determine time since death. Top Keywords Forensic medicine, Pupillary miotic change, Pilocarpine eye drop, Time since death. Top |