Can Hypocalcaemia Predict Adverse Outcome in Malaria?-Preliminary Data From Tertiary Care Centre in Western India Sahay Ravindranath1, Joshi Kavita S2,* 1Professor (Addl), Department of Medicine, Seth G S Medical College, Parel, Mumbai, Maharashtra, India 2Associate Professor, Department of Medicine, Seth G S Medical College, Parel, Mumbai, Maharashtra, India Corresponding author: Kavita S Joshi Associate Professor, Department of Medicine, Seth G S Medical College, Parel, Mumbai, Maharashtra-400012, India Contact No.: 9869788359 E-mail: kavitajoshi@kem.edu
Online published on 15 December, 2017. Abstract Background In India total economic burden from malaria could be around US$ 1940 million. This study aims to find with the prevalence of hypocalcaemia in the different types of malaria, whether it has any relevance to the clinical presentation of the disease. Method It was a prospective observational study done in tertiary care centre over a period of 3 months. Patients more than 12 years of age and confirmed cases of malaria on thick and thin smear examination were included in the study. Treatment was given as per standard protocol and as per discretion of treating physician. Serum calcium levels and ECG were done with all other baseline biochemistry of patient. Results Severity of presentation, QTc prolongation, hypotension and complicated malaria were compared with presence and absences of hypocalcaemia all were(using chi square test X2)statistically significant. Abnormal Renal function, liver function and coagulation profile were found to have no correlation with hypocalcaemia. Conclusions This study is showing that patients who have hypocalcaemia tend to present in critical condition, have hypotension, prolonged QTc and tend to complicate. Top Keywords Malaria, Hypocalcaemia, Prognosis, QTc. Top |