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Cytotoxic activity of Alphonsea sclerocarpa bark extract Prasad Dasari Narendra Dept. of Pharmacognosy, Nalanda College of Pharmacy, Cherlapally, Nalgonda, Andrapradesh, India *Corresponding Author: Dasari Narendra Prasad, Dept. of Pharmacognosy, Nalanda College of Pharmacy, Cherlapally, Nalgonda, Andrapradesh, India E-mail: talktonarender@gmail.com
Online published on 22 March, 2013. Abstract Invitro cytotoxic activity of Alphonsea sclerocarpa has been investigated by tryphan blue dye exclusion method at various concentration on Ehlirich Ascites Carcinoma cells. The ethanolic extracts of Alphonsea sclerocarpa has showed the significant cytotoxic property by inhibiting the dye exclusion was evaluated by comparing with standard 5-Fluorouracil. The preliminary study indicates the ethanolic extract of Alphonsea sclerocarpa has significant cytotoxic property and suggests for further investigation for its antitumor and anticarcinogenic function in different models. Top Keywords Alphonsea sclerocarpa, Cytotoxic activity, EAC cells, 5fluorouracil. Top | |
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