Comparative diagnosis of canine mammary tumours by cytology and histopathology Acharya A.T.1, Ghodasara D.J.1, Joshi B.P.1, Dave C.J.1, Prajapati K.S.1, Jani Purnima B.1, Khorajiya J.H.1,* 1Department of Veterinary Pathology, College of Veterinary Science and Animal Husbandry, AAU, Anand-388001, Gujarat, India *Corresponding author: e-mail: jainudeen_1990@rediffmail.com
Abstract The aim of the present study was to correlate cytological diagnosis after pre-operative fine needle aspiration biopsies from canine mammary tumours with that of histopathological findings. In prospective study, 40 fine-needle aspirate samples were obtained from 40 different cases, out of that, 15 cases were diagnosed mammary gland tumours. Histopathology results included four cystic papillary adenoma, three benign mixed mammary tumours, two each of papillary adenocarcinoma, solid adenocarcinoma, and mammary gland adenoma, and one each of benign mammary myoepithelioma and malignant myoepithelioma. The neoplastic cells in smears were round to caudate, exhibiting anisocytosis, spherical to oval nuclei, anisokaryosis, abnormal nuclear/nucleolar shapes, anisonucleoli, abnormal chromatin pattern, multinucleation and mitotic figures. In case of benign category cells were uniform and in large clusters, having clear cytoplasmic boundaries. On comparing results of cytological diagnosis with the histopathology revealed that 86.66% (13/15) cases of benign and malignant tumours had positive correlation. Top Keywords FNAC, Cytology, Canine, Histopathology, Mammary tumour. Top |